PNAS Nexus is an open access scientific journal focused on the publication of high-quality, impactful research with broad, interdisciplinary appeal. Published by the National Academy of Sciences (NAS) in partnership with Oxford University Press, PNAS Nexus is committed to the timely dissemination of innovative and scientifically rigorous research from across the biological, medical, physical, social, and political sciences, and engineering and mathematics. All articles are freely and publicly available to read and reuse.